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氯诺西康复合小剂量舒芬太尼用于妇科术后患者静脉自控镇痛
Postoperative patient-controlled intravenous analgesia with lornoxicam injection combined with low dose sulfentanyl in patients undergoing gynaecological surgery

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DOI:
作者:
施美新 尤新民
SHI Meixin, YOU Xinmin.
作者单位:
新华医院崇明麻醉科 上海市崇明县南门港街25号
Department of Anesthesiology, Xinhua Hospital (zhang ming),Shanghai Jiaotong University School of Medicine,Shanghai 202150, China
关键词:
【关键词】氯诺昔康 舒芬太尼 患者自控镇痛 子宫切除术
【Key words】lornoxicam; sulfentanyl; patient-controlled analgesia; hysterectomy
摘要:
氯诺昔康复合小剂量舒芬太尼用于妇科术后患者静脉自控镇痛 施美新 尤新民 【摘要】目的 评价氯诺昔康复合小剂量舒芬太尼用于妇科手术后患者静脉自控镇痛（PCIA）的临床效果。方法 选择性行妇科子宫切除术患者80例，ASAⅠ-Ⅱ，随机分两组，组Ⅰ为氯诺昔康32mg、舒芬太尼0.1mg，组Ⅱ为舒芬太尼0.2mg，各加入0.9％氯化钠至100ml。术毕组Ⅰ静脉注入氯诺昔康8mg，组Ⅱ静脉注入舒芬太尼5ug，连接镇痛泵，背景剂量2ml/h，PCA为0.5ml，锁定时间为15min。观察术后48h的VAS评分、PCA按压总次数和不良反应的发生情况。结果 两组镇痛观察期间各时间点VAS评分、PCA按压总次数组间比较差异无统计显著性(P>0.05)，组Ⅰ的不良反应明显低组Ⅱ，差异显著性（P<0.05）。结论 氯诺昔康复合小剂量舒芬太尼用于妇科手术后镇痛效果确切、不良反应发生率低。 【关键词】氯诺昔康 舒芬太尼 患者自控镇痛 子宫切除术
Postoperative patient-controlled intravenous analgesia with lornoxicam injection combined with low dose sulfentanyl in patients undergoing gynaecological surgery SHI Meixin, YOU Xinmin. Department of Anesthesiology, Xinhua Hospital (zhang ming),Shanghai Jiaotong University School of Medicine,Shanghai 202150, China CorrespondingauthorYOU.Xinmin. E-mail:babayouxinmin@hotmail.com 【Abstract】 Objective To assess analgesic efficaey lornoxicam injection combined with low dose of sulfentanyl for patient-controlled intravenous analgesia(PCIA) in patients undergoing gynaecologcal surgery. Methods Eighty patients undergoing elective abdominal hysterectomy surgery, ASAⅠ-Ⅱ, They were evenly randonized into two groups, The analgesic mixture in group Ⅰconsisted of lornoxicam 32mg`and sulfentanyl 0.1mg, in groupⅡconsisted of sulfentanyl 0.2mg in 100mL Nacl, respectively. The end operation, group Ⅰreceived lornoxicam 8mg and group Ⅱreceved sulfentanyl 5ug.The PCIA pump was set up with a bolus of 0. 5ml and lockout interval was 15 min with a background 2ml infusiom. The visual analog scole(VAS),times of patient-controlled analgesia(PCA) and incidence of side effects were observed during 48 hours after operation.Results There were no statistical difference in VSA and PCA times two groups during ganalgesia(all P>0.05), The incidence of side effects in group Ⅰwere signicantly less than in group Ⅱ(all P<0.05).Conclusion PCIA with lornoxicam injection combined with low dose sulfentanyl in patients undergoing hysterectomy surgery can achieve satisfactory analgesia and reduce sulfentanyl dose and its related side effects. 【Key words】lornoxicam; sulfentanyl; patient-controlled analgesia; hysterectomy

 

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