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上海市卫生健康委员会
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超声显示钙化对甲状腺良恶性结节鉴别的临床意义
Clinical value of sonographic calcification in the identification of thyroid nodules

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DOI:
作者:
杨洁瑾
Yang Jjiejin
作者单位:
上海瑞金医院卢湾分院内分泌科
Department of Endocrinology, Shanghai Ruijin Hospital Luwan Branch,Shanghai Jiaotong University School of Medicine
关键词:
超声检查，甲状腺结节，钙化，微钙化
ultrasound, thyroid nodules, calcification,microcalcifications
摘要:
【摘要】目的：探讨甲状腺超声探查中显示的钙化灶对甲状腺结节良恶性鉴别的临床意义。材料和方法：347例行甲状腺手术患者的病理与其术前甲状腺彩色多普勒超声图像的回顾性分析。结果：恶性组钙化率（69.6%）及微钙化率（45.1%）显著高于良性组，且≤45岁患者恶性甲状腺结节钙化率为81.6%，微钙化率达到68.4%，与＞45岁患者相比具有显著统计学差异。结论：超声图像中的钙化是甲状腺癌的一项特异性指标，一旦发现甲状腺内有钙化病灶，尤其为微钙化，年龄小于45岁且伴较大结节者，应该高度警惕癌变风险。
[Abstract] Objective: The purpose of this study is to investigate the significance of ultrasound of thyroid calcification shown in the identification of benign and malignant nodules. Methods: The sonographical and pathological data were studied retrospectively from 347 patients who underwent thyroidectomy by color doppler ultrasound. Results: The rate of malignant calcification (69.6%) and microcalcification rate (45.1%) was significantly higher than benign group, and ≤ 45-year-old patient from malignant thyroid nodule calcification was 81.6%, microcalcification rate of 68.4%, the differences were statistically significant conpared with> 45-year-old patient. Conclusion: The ultrasound image of the thyroid calcification is a specific marker for thyroid cancer. Especially for the microcalcification while the patients are less than 45-year- age and with larger nodules, we should be aware of the possibility of malignant transformation.

 

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