注册本刊作者作者投稿查稿
专家远程审稿编辑在线审稿
编务办公专区主编办公专区
下载文档
工作动态
联系方式
发行周期:
月刊
主管单位:
上海市卫生健康委员会
主办单位:
上海市医学会
编辑出版:
《上海医学》编辑部
联系地址:
上海市北京西路1623号
邮编:
200040
电话:
021-62178606
传真:
021-62178606
邮箱:
smasmj@shsma.org.cn
ISSN:
ISSN0253-9934
CN:
CN31-1366/R
收款账号:
1001255309008900719
账户名:
上海市医学会
开户行:
工商银行上海市静安寺支行
友情链接

当前位置：首页 > 过刊浏览->2011年第10期

雷莫斯琼预防口腔颌面外科术后恶心呕吐的临床效果

浏览(2521) 下载(0)

DOI:
作者:
黄燕，姜虹，朱也森
Huang Yan, Jiang Hong, Zhu Yesen
作者单位:
上海交通大学医学院附属第九人民医院麻醉科
Department of Anesthesiology, The 9th People Hospital, The Shanghai Jiaotong University, School of Medicine
关键词:
雷莫司琼；口腔颌面外科；经静脉患者自控镇痛；术后恶心呕吐
ramosetron；oral and maxillofacial surgery； patient-controlled intravenous analgesia (PCIA)； Postoperative nausea and vomiting (PONV)
摘要:
【摘要】 目的 比较雷莫司琼与昂丹司琼在预防口腔颌面外科术后恶心呕吐的疗效。方法 择期行口腔颌面外科手术患者120例，ASAⅠ～Ⅱ级，年龄23～72岁，随机分为3组（n=40），雷莫司琼组（A组)：麻醉诱导前静脉给予雷莫司琼2ml（0.3mg），术后镇痛微量泵中加入0.3mg/2ml；昂丹司琼（B组)：麻醉诱导前静脉给予昂丹司琼4mg/2ml，术后镇痛微量泵中加入4mg/2ml；生理盐水对照组（C组)：麻醉诱导前给予生理盐水2ml, 术后镇痛微量泵中加入生理盐水2ml：。结果 与C组比较，A组和B组术后恶心呕吐发生率和严重程度发生率显著降低（P<0.05）；与B组比较，A组恶心呕吐的发生率和严重程度明显下降（P<0.05）。结论 雷莫司琼能有效预防口腔颌面外科术后的恶心呕吐.
[Abstract] Objective To compare the efficacy of ramosetron and ondansetron on prevention the postoperative nausea and vomiting (PONV) in patients undergoing oral and maxillofacial surgery. Methods A total of 120 patients ,ASAⅠ～Ⅱ,aged from 23 to 72 years old were involved in this study. All patients received general anesthesia and patient-controlled intravenous analgesia (PCIA),who were randomly divided into 3 groups(n=40): ramosetron group(group A): before anesthesia induction ,the patients were given 0.3mg/2ml ramosetron, and another 0.3mg/2ml ramosetron was added into PCIA; ondansetron group B(group B):4mg/2ml ondansetron was given before anesthesia induction, and another 4mg/2ml ondansetron was in PCIA; placebo group (group C):2ml normal saline was given before anesthesia induction and into PCIA . Results The incidence of PONV and severity was significantly lower in group A and group B than that in group C, compared with group B（P<0.05）,the incidence and severity of PONV was clearly decreased（P<0.05）.Conclusion Ramosetron could effectively protect patients undergoing oral and maxillofacial surgery from PONV.

 

主管单位：上海市卫生健康委员会  主办单位：上海市医学会
©2024《上海医学》编辑部 沪ICP备09078599号
您是本站第26557142名访问者
网站管理