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光学断层成像中乳酸林格氏灌注液对中华小型猪心肌损伤的影响
The security and image quality of optical coherence tomography during which using Lactated Ringer'S Solution as perfusate in Chinese mininature pigs
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DOI:
作者:
许嘉鸿
Xu Jiahong
作者单位:
同济大学附属同济医院心内科
Cardiology Dept. Tongji Hospital of Tongji University
关键词:
光学相干断层成像 乳酸林格氏液 灌注液
Optical coherence tomography, Lactated Ringer'S Solution, Perfusate
摘要:
目的 探讨光学相干断层成像(optical coherence tomography, OCT)中以乳酸林格氏液代替生理盐水进行灌注对成像质量及检查安全性的影响。方法 取20例中华小型猪为研究对象,随机分组后进行OCT检查。术中灌注液分别用生理盐水和乳酸林格氏液,记录术中心电图,检测术后心肌酶及心肌病理切片,比较两者的安全性和成像质量区别。结果 对照组死亡率、术中室颤发生例数、术后心肌酶学升高例数以及病理切片心肌坏死明显低于试验组。而两组OCT成像质量之间无明显差异。结论 在OCT检查时,用乳酸林格氏液代替生理盐水进行灌注,能较好的保护缺血心肌,降低OCT检查时的并发症。
Objective To investigate the security and image quality of optical coherence tomography during which using Lactated Ringer'S Solution as perfusate instead of physiological saline. Methods OCT images were obtained in 20 Chinese mininature pigs randomly. Lactated Ringer'S Solution or physiological saline were used as perfusate in the examinations. The pigs'ECG, cardiac enzymes and cardical pathological section were acquired to compare the security and image quality of the two perfusates. Results The incindence of death, ventricular fibrillation and rise of cardiac enzymes were lower in the Lactated Ringer'S Solution group than in the physiological saline group. The cardical pathological sections also showed that the size of myocardial necrosis were smaller in the Lactated Ringer'S Solution group than in the physiological saline group. Yet the image quality of optical coherence tomography had no difference. Conclusions Using Lactated Ringer'S Solution as perfusate instead of physiological saline in OCT examination can protect the ischemic myocardium and reduce the incidence of complications.
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