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交感神经阻滞治疗带状疱疹后遗神经痛
Treatment of Postherpetic Neuralgia by sympathetic nerve block.
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DOI:
作者:
李浪平
Li Langping
作者单位:
上海市嘉定区中医医院
Jiading Hospitsl of Traditional Chinese Medicine
关键词:
交感神经阻滞, 带状疱疹后遗留神经痛, 痛觉过敏
Sympathetic nerve block; Postherpetic Neuralgia; Hyperaesthesia
摘要:
目的 观察交感神经阻滞治疗带状疱疹后遗神经痛的临床疗效。方法 选择带状疱疹后遗痛的患者64例,随机分为对照组(A组)和治疗组(B组)。A组(n=26)采用药物治疗(部分治疗效果不明显者即刻退出试验观察,改用交感神经阻滞治疗)。B组在药物治疗基础上,采用交感神经阻滞治疗(n=29)。采用视觉模拟评分法(VAS法)分别评估治疗前、治疗后1周、治疗疗程结束时及疗程结束后3月的VAS评分,以及伴随症状的改善情况和并发症。结果 治疗后1周、疗程结束时及结束后3月时,两组VAS评分均较治疗前明显降低(P<0.01),但B组上述时间点的VAS评分较A组显著降低(P<0.01)。两组患者的麻木、痛觉过敏、睡眠障碍、焦虑等症状均有一定改善,但B组的有效率高于A组(P<0.05)。结论C臂机引导下对受损部位进行交感神经阻滞治疗,对带状疱疹后遗神经痛有明显的疗效。
Objective To explore the effect and safety of sympathetic nerve block in the treatment of Postherpetic Neuralgia(PHN). Methods 64 patients with PHN were randomly divided into control group (group A, n=26) and treatment group (group B, n=29). Patients in the group A only received medicine treatment, while patients in the group B received sympathetic nerve block on the basis of medication. VAS evaluation, patients’ subjective evaluation was assessed and side effects were observed before treatment, one week after treatment, treatment finished and three months after treatment. Results Compared with pretreatment, VAS significantly decreased at 1 week after treatment、treatment finished and 3 months after treatment in both groups (P<0.01). Compared with the group A, VAS in the group B was significantly lower at 1 week after treatment、treatment finished and 3 months after treatment (P<0.01). The symptoms, including numbness, hyperalgesia, hyperaesthedia, sleep dysfunction and anxiety, were improved in both groups. However, the effect in the group B was much better than that in the group A(P<0.05). Conclusion sympathetic nerve block has a significant effect on Postherpetic neuralgia.
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