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氟比洛酚酯超前镇痛时机对妇科腹腔镜术后镇痛效果的影响
The analgesia effects of the time using flurbiprofen axetil for preemptive analgesia after gynecologic laparoscopic surgery
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DOI:
作者:
安小虎
AN XIAOHU
作者单位:
上海国际和平妇幼保健院
Internatial peace maaternity and child health hosptial affiliated to shanghai Jiaotong university school of medicine,Shanghai 200030
关键词:
氟比洛酚酯 超前镇痛 妇科腹腔镜手术
flurbiprofen axetil preemptive analgesia gynecologic laparoscopic operation
摘要:
【摘要】 目的 观察氟比洛酚酯超前镇痛时机对妇科腹腔镜术后镇痛效果的影响;方法 择期行妇科腹腔镜手术的患者共120例,被随机均分为三组,每组40例;A组:麻醉诱导前静脉注入氟比洛芬酯100mg;B组:手术结束后静脉注入氟比洛芬酯100mg;C组:空白对照组;术后用视觉模拟评分法(VAS)对拔管后即刻、1、4、8、12 、24 hr的切口痛、内脏痛进行评分,并记录术后镇痛药使用的时间、人数和使用的次数。结果 A、B两组在术后12hr内VAS评分均低于C组;和B组比较,A组在拔管后即刻VAS评分略低,但没有统计学意义;而三组在12hr后评分差异无显著性。三组患者术后需要镇痛药物治疗的例数差异有统计学意义;结论 氟比洛酚酯超前镇痛用于妇科腹腔镜手术,术后镇痛效果显著,但术前、术后给药的镇痛效果相似。
The analgesia effects of the time using flurbiprofen axetil for preemptive analgesia after gynecologic laparoscopic surgery AN XiaoHu ,XU Tao,YU DaSong. Department of Anesthesia, The International Peace Maternity & child Health Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200030 [ Abstract ] Objective To observe the analgesia effects of the time using flurbiprofen axetil for preemptive analgesia after gynecologic laparoscopic surgery. Methods 120 Patients, undergoing selective gynecological laparoscopic operation, were randomly divided into A,B and C group (40 cases each group).In group A, patients were injected intravenously with flurbiprofen axetil 100mg before induction of anesthesia; In group B, patients were injected intravenously with flurbiprofen axetil 100mg after gynecologic laparoscopic surgery. Group C was the control group. Using visual analogue score ( VAS ) , the incision pain and visceral pain were observed at the time of postoperative extubation immediately, 1, 4, 8, 12, 24hr. The number of the need for postoperative analgesic, the frequency and the use of time were recorded. Results The VAS score of group A and group B were significantly lower than that in group C before 12hr; Compared with group B, the VAS score of group A was slightly low after extubation immediately, but no statistical significance; The VAS score of three groups had no significant difference after 12hr. The number of the need for postoperative analgesic and the using times in three groups were2/2、2/3、9/11, in groups C,the cases of treated patients were more than that of A and B group, the difference was statistically significant. Conclusion Preemptive analgesia of flurbiprofen axetil for gynecological laparoscopic surgery is significantly effective. Whether preoperative or postoperative using flurbiprofen axetil for preemptive analgesia after gynecologic laparoscopic surgery, they were similar effects.
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