首页
期刊简介
编 委 会
期刊订阅
百年学会 医星璀璨
名院风范
学科风华
菁英风采
投稿须知
过刊浏览
联系我们
篇名
关键词
作者
作者单位
摘要
关键词
注册本刊作者
作者投稿查稿
专家远程审稿
编辑在线审稿
编务办公专区
主编办公专区
下载文档
《上海医学》审稿费代缴委托书
《上海医学》杂志2024年征订启事
《上海医学》期刊编审系统审稿专家使用手册
工作动态
03-05
《上海医学》杂志2024年度“春蕾杯”论文评比征文通知
06-14
创新驱动,培育人才—《上海医学》2021年度春蕾计划评审结果揭晓
01-21
《上海医学》期刊影响力指标和学科排名取得显著提升
01-20
《上海医学》恭祝大家新年快乐!
08-18
作废声明
联系方式
发行周期:
月刊
主管单位:
上海市卫生健康委员会
主办单位:
上海市医学会
编辑出版:
《上海医学》编辑部
联系地址:
上海市北京西路1623号
邮编:
200040
电话:
021-62178606
传真:
021-62178606
邮箱:
smasmj@shsma.org.cn
ISSN:
ISSN0253-9934
CN:
CN31-1366/R
收款账号:
1001255309008900719
账户名:
上海市医学会
开户行:
工商银行上海市静安寺支行
友情链接
上海市医学会
当前位置:首页 >
术前经鼻使用右美托咪定对行腺样体扁桃体切除术患儿的临床效果观察
Observation of the clinical effects of Dexmedetomidine for intranasal premedication in pediatric patients undergoing adenotonsillectomy
浏览(502) 下载(0)
DOI:
作者:
赵娣,王英伟
Di Zhao, Yingwei Wang
作者单位:
上海交通大学附属新华医院麻醉科 上海交通大学附属新华医院麻醉科
Department of Anesthesiology and Critical Care Medicine,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Department of Anesthesiology and Critical Care Medicine,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
关键词:
脑电双频指数,右美托咪定,小儿,鼾症,躁动
BIS, Dexmedetomidine, Pediatric, Emergency agitation, OSAHS
摘要:
目的 观察术前经鼻使用右美托咪定对患有阻塞性呼吸暂停低通气综合征患儿的围术期镇静效果、血流动力学和脑电双频指数(BIS)的影响。方法 选取56例将行腺样体扁桃体切除术的患儿,随机分为两组:C组为对照组,经鼻予以生理盐水(NS)0.01ml/kg;D组为右美托咪定组,经鼻予以右美托咪定1μg/kg。在用药前后、麻醉诱导后及苏醒期共23个时间点监测患儿的基础生命体征(HR、SpO2、MAP)及BIS值。在插管前,监测患儿的Ramsay镇静评分和合作评分。手术结束后评价全麻效果,并进行Steward评分及镇静、躁动评分。结果 C组患儿的心率及平均动脉压多个时间点显著高于D组,差异有统计学意义(P<0.05),两组间脉氧饱和度值差异无统计学意义;插管前C组的BIS值多个时间点显著高于D组,差异有统计学意义(P<0.05),插管后及术后两组的BIS值差异无统计学意义;插管前C组与D组Ramsay评分及合作评分差异有统计学意义(P<0.05);插管时肌松程度及全麻效果差异无统计学意义;术后苏醒期C组与D组的清醒程度,steward评分及镇静、躁动评分差异无统计学意义。结论 术前经鼻使用右美托咪定可使患儿术前合作程度提高,减少术中血流动力学波动,但并不能减少术后躁动的发生率。
Objective To observe the clinical effects of intranasal premedication of Dexmedetomidine conducts in pediatric patient undergoing adenoldectomy, including sedation, hemodynamics and BIS index. Methods 56 patients undergoing adenotonsillectomy were enrolled and randomly assigned to two groups: C group(saline 0.01ml/kg) and D group (Dexmedetomidine1μg/kg). During the entire research process, we chose 23 time points for recording the basic vital signs,including heart rate(HR),SpO2, mean arterial pressure(MAP) and BIS index. Ramsay sedation scores and Cooperation scores were valued before intubation. Awake scores, Steward scores and Sedation-Agitation Scale were valued after the operation. Muscle relaxation and intubation conditions were also valued. Results The HR and MAP of C group were higher than that of D group in 15 and 9 time points, P<0.05. SpO2 had no statistical difference. Bis index of C group were higher in 5 time points before intubation, P<0.05. Ramsay sedation scores and Cooperation scores were different in two groups before intubation, P<0.05. Muscle relaxation, intubation conditions, Awake scores, Steward scores and Sedation-Agitation Scale after the operation had no statistical differences. Conclusion Intranasal premedication of Dexmedetomidine can increase the degree of cooperation and reduce the hemodynamic fluctuations, but has no effect on the incidence of emergency agitation.
点击下载DOC全文