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地佐辛超前镇痛在妇科腹腔镜手术中的应用1
Effects of Dezocine on Preemptive Analgesia in Patients with Laparoscopic Gynecological Surgery
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DOI:
作者:
胡韵佳,全顺姬,李志高,翟东
Hu Yun-jia,Quan Shun-ji,Li Zhi-gao,Zhai Dong
作者单位:
中国人民解放军第八五医院 麻醉科
Department of Anesthesia,No.85 Hospital of PLA
关键词:
地佐辛;超前镇痛;腹腔镜手术
dezocine; preemptive analgesia; laparoscopic operation
摘要:
【摘要】目的:探讨地佐辛超前镇痛在妇科腹腔镜手术中的应用效果。方法:选择择期行妇科腹腔镜手术患者60例,随机分为实验组和对照组各30例。所有患者均选用气管插管全身麻醉,实验组于麻醉诱导前5min静脉缓慢注射地佐辛0.1mg/kg(用生理盐水稀释至5ml),对照组注射等量生理盐水。观察并比较两组患者围拔管期的躁动程度(镇静躁动评分SAS),术后5min,30min,1h,2h,4h,6h的镇痛评分(VAS疼痛评分),并发症的发生率及杜冷丁的使用情况。结果:实验组围拔管期镇静躁动评分(SAS),术后5min和30minVAS评分均无统计学差异,而术后1h、2h、4h、6hVAS评分明显低于对照组,差异有统计学意义(P<0.05)。实验组较对照组使用杜冷丁镇痛的比例明显降低,差异有统计学意义(P<0.05),且术后使用杜冷丁的时间一般在术后6小时左右。其他并发症发生率无统计学差异。结论:妇科腹腔镜手术麻醉诱导前5min使用地佐辛,可以有效减轻患者的术后疼痛,降低术后镇痛药物使用率,且无明显不良反应。
[Abstract] Objective To explore the effect of dezocine on preemptive analgesia in patients with laparoscopic gynecological surgery. Methods 60 patients undergoing laparoscopic gynecological surgery were randomly divided into the study group(n=30) and the control group(n=30). Both groups received general anesthesia.5 minutes before anesthesia induction ,the study group received intravenous dezocine of 0.1 mg / kg (diluted with normal saline to 5ml), while the control group was injected with the same amount of saline at the same time. Recorded the agitation degree in extubation periods (sedation agitation score,SAS), postoperative 5min, 30min, 1h, 2h, 4h, 6h pain score (VAS), adverse reaction rates and the usage of pethidine. Results During the extubation period,the sedation agitation scale (SAS) and the VAS score at 5 min and 30min after operation of the study group had no significant statistical difference, but the VAS score at 1h, 2h, 4h, 6h after operation in study group were significantly lower than that of control group (P < 0.05). The usage of pethidine in the study group was lower than that of control group(P < 0.05) ,and we always used pethidine at about 6 hours after operation. No significant statistical difference in the incidence of other adverse reactions. Conclusion The usage of dezocine at 5 minutes before anesthesia induction in the laparoscopic gynecological surgery can effectively relieve patients postoperative pain, reduce postoperative analgesia drug use, and no obvious adverse reactions.
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